New England Journal of Medicine published two articles on vitamin D supplements today (2022-7-28). Research article: Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults Editor review: VITAL Findings — A Decisive Verdict o...
New England Journal of Medicine published two articles on vitamin D supplements today (2022-7-28).
Research article: Supplemental Vitamin D and Incident Fractures in Midlife and Older AdultsEditor review: VITAL Findings — A Decisive Verdict on Vitamin D Supplementation (the most important discovery of — — deterministic judgment on vitamin D supplements).
The first author of the research paper is Dr. Meryl Susan LeBoff. She is a professor at Harvard University and director of the Center for Bone Relief. Several of the other 12 authors are also weight-level, such as JoAnn Manson, director of the Center for Preventive Medicine at Harvard University.
Research Machine: Vitamin D supplements are widely recommended to the general population as a means to promote bone health. Between 1999 and 2012, the proportion of vitamin D supplements used by American adults increased from 5.1% to 19%. However, data on whether these supplements prevent fractures are contradictory. System ratings and scallion analysis of random-control trials raise questions about whether vitamin D supplementation is beneficial for first-level prevention of fractures. In 2021, the U.S. Preventive Services Work Group found that supplemental vitamin D had no effect on fracture incidence in community adults with low 25-regular vitamin D levels. The Institute of Medicine found that fracture risk increased at low and high levels of 25-regular vitamin D and stressed the need for more research from large random control trials. To understand these knowledge gaps, we examined whether vitamin D3 supplementation reduces the risk of fractures in overall healthy American adults in a large vitamin D and Omega-3 trial (VITAL) assisted study.
Research subjects: The 25,871 participants recruited from the United States were about half a woman, with men and half aged over 50 years old and women over 55 years old. They were randomly assigned to two groups, with 12,927 trial groups and 12,944 counterparts. The trial group took 2,000 vitamin D supplements a day, while the conscription group took comforters a day. I ate it for about 5 years and 4 months.
Results:
1. Total fractures: 769 trial groups, 782 control groups2. Non-spine fractures: 721 trial groups, 744 control groups
3. Haemostric fractures: 57 trial groups, 56 control groups
Conclusion: Vitamin D3 supplementation did not significantly reduce the risk of fractures compared with consolation agents. There are two authors in that editorial review. Dr. Steven Cummings is a professor at the University of California, San Francisco and an expert in bone relieving disorders. Dr. Clifford Rosen is director of the Clinical and Transformation Research Center at the Myanmar Medical Center and an expert on Vitamin D.
The final paragraph of this review, which they co-written is: "Vitamin D does not affect fractures. This should dispel any notion of single use of vitamin D to prevent fractures. These findings, combined with previous VITAL clinical trials, and several other clinical trials, suggest that 25-Radian vitamin D levels or recommended vitamin D supplements should be stopped. People should stop taking vitamin D Replenishing agents can prevent serious illness or prolong life. ”
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Original text: Deterministic judgment: Stop taking vitamin D supplement